22 April 2021
My role is to evaluate plants and fungi and their constituent compounds for their potential as medicines. I’m currently working with communities in remote rainforest areas of Papua New Guinea to try and find an easily accessible, clinically effective plant medicine to treat tropical ulcers. A second research area is simplified yeast chemical genetic assays to rapidly determine the modes of action of antifungal plant compounds; these assays can be reconfigured to look at specific human drug targets.
- Antiviral proof of concept project (Edinburgh Technology Fund), 2006
- PhD, Univ. Edinburgh, 2005
- BSc (Hons), Univ. Edinburgh, 1999
Prescott, T. A. K., Homot, P., Lundy, F.T., Fang, R., Patrick, S., Cámara-Leret, R., Kiapranis, R. (2017).
Journal of Ethnopharmacology 205: 240-245.
Prescott., T. A. K., Panaretou, B. A. (2017).
A mini HIP HOP assay uncovers a central role for copper and zinc in the antifungal mode of action of allicin.
Journal of Agricultural and Food Chemistry 65: 3659-3664.
Pinheiro, A, M., Carreira, A., Prescott, T.A.K., Ferreira, R, B., and Monteiro, S. A. (2017).
Bridging the gap to non-toxic fungal control: Lupinus-derived BLAD-containing oligomer as a novel candidate to combat human pathogenic fungi
Frontiers in Microbiology 8: 1182.
Prescott, T. A. K., Panaretou, B., Veitch, N. C. & Simmonds, M. S. (2014).
A yeast chemical genetics approach identifies the compound 3,4,5-trimethoxybenzyl isothiocyanate as a calcineurin inhibitor.
FEBS letters 588: 455-458.
Prescott, T. A. K., Kite, G. C., Porter, E. A., Veitch, N. C. (2013).
Highly glycosylated flavonols with an O-linked branched pentasaccharide from Iberis saxatilis (Brassicaceae).
Phytochemistry 88: 85-91.