Dr Eduard Mas-Claret
Post-doctoral Researcher
Department
Team
Specialism
Organic chemistry, natural products, computational chemistry, identification of novel bioactive compounds, pyrethrins
Pyrethrins extracted from the flowers of Tanacetum species, pyrethrum, is the most important global plant-based pesticide. My role focuses on the development of new and efficient extraction methods and new formulations that replace synthetic and toxic components of pyrethrum with sustainable alternatives, aiming to improve organic pest management applied to African agriculture but with global appeal.
In addition to my work on pyrethrum, my research is based on the identification of novel biochemicals from natural products, using techniques such as nuclear magnetic resonance and high-resolution mass spectrometry, but also focusing on computational methods to establish their structures.
- PhD, Univ. Surrey, 2018
- MSc, Univ. Surrey, 2014
- BSc (Hons), IQS School of Engineering, 2013
Isyaka, S. M., Mas-Claret, E., Langat, M. K., et al. (2020)
Cytotoxic diterpenoids from the leaves and stem bark of Croton haumanianus (Euphorbiaceae).
Phytochemistry 178: 112455.
Munissi, J. J. E., Isyaka, S. M., Mas-Claret, E., et al. (2020).
Ent-clerodane and ent-trachylobane diterpenoids from Croton dictyophlebodes.
Phytochemistry 179: 112487.
Langat, M. K., Djuidje, E. F. K., Ndunda, B. M., Isyaka, S. M., Dolan, N. S., Ettridge, G. D., Whitmore, H., Lopez, I., Alqahtani, A. M., Atiku, I., Lobe, J. S., Mas-Claret, E. et al. (2020).
The phytochemical investigation of five African Croton species: Croton oligandrus, Croton megalocarpus, Croton menyharthii, Croton rivularis and Croton megalobotrys.
Phytochemistry Letters 40: 148-155.
Mas Claret, E., Al Yahyaei, B., Chu, S. et al. (2020).
An aza-nucleoside, fragment-like inhibitor of the DNA repair enzyme alkyladenine glycosylase (AAG).
Bioorganic & Medicinal Chemistry 28: 115507.
Schwikkard, S., Whitmore, H., Sulaiman, R. S., Sishtla, K., Shetty, T., Basavarajappa, H. D., Waller, C., Alqahtani, A., Frankemoelle, L., Chapman, A., Crouch, N., Wetschnig, W., Knirsch, W., Andriantiana, J., Mas-Claret, E., Langat, M. K., Mulholland, D. A., & Corson, T. W. (2019)
The Antiangiogenic Activity of Naturally-occurring and synthetic Homoisoflavonoids from the Hyacinthaceae (sensu APGII)
Journal of Natural Products 82: 1227–1239.