Dr Rui Fang

Project Staff: Natural Product Chemist

Rui Fang
Biography Plus

I use my knowledge in natural products and their biological activities to further our knowledge about the traditional uses of plants and fungi. This involves using in-vitro bioassay-guided fractionation methods to isolate active compounds to support the scientific basis of their uses. Structures of compounds are determined using Liquid Chromatography-Mass SpectrometryS/Mass Spectrometry and Nuclear Magnetic Resonance techniques. My focus has been on using multivariate data analysis technologies to analyse data sets that combine chemical and biological data. I use these techniques to not only differentiate among species and within samples from a species to identify those that contain high levels of active compounds.  This enables me evaluate the quality of natural products entering the trade, especially for use in food, cosmetics and healthcare products.  I collaborate with colleagues to develop these cross-disciplinary data mining methods to maximise the use of our collections in providing a robust scientific understanding of plant and their uses. 

Qualifications and appointments Plus
  • BSc / Biochemistry, South China Agricultural University 2001
  • PhD / Pharmacy, King’s College London, University of London 2006
  • Research Associate, Pharmacy department, King’s College London 2007
Selected publications Plus

Rui, F., Veitch, N.C., Kite, G.C., Porter, E.A., Simmonds, M.S.J. (2013) 

Enhanced Profiling of Flavonol Glycosides in the Fruits of Sea Buckthorn (Hippophae rhamnoides)

Journal of Agricultural and Food Chemistry  61: 3868−3875. Available online

Fang, R., Veitch, N.C., Kite, G.C., Howes, M-J.R., Porter, E.A. & Simmonds, M.S.J. (2011)

Glycosylated constituents of Iris fulva Ker Gawl. and Iris brevicaulis Ra

Chemical & pharmaceutical Bulletin 59(1): 124-128. Available online

Fang, R., Houghton, P.J. & Hylands, P.J. (2008)

Cytotoxic effects of compounds from Iris tectorum on human cancer cell lines

Journal of Ethnopharmacology 118(2): 257-263. Available online

Fang, R., Houghton, P.J. , Luo, C. & Hylands, P.J. (2007)

Isolation and structure determination of two triterpenes from Iris tectorum

Phytochemistry68(9): 1242-1247. Available online

Fang, R. (2005)

The principles and methods for the development of TCM quality control system

Chinese Journal of Information on Traditional Chinese Medicine 12(6): 3-5. Available online