Simmonds, Monique

Job Title

Director of the Kew Innovation Unit, Deputy Keeper & Head of Sustainable Uses of Plants Group

Department

Jodrell Laboratory

Section

Sustainable Uses

Science Teams:

Joined Kew:

1985

Qualifications & Appointments

BSc (Hons), Univ. Leeds

PhD, Birkbeck College, Univ. London

Fellow Royal Society of Entomology

Fellow World Innovation Foundation

Fellow of the Society of Biology

Fellow of the Linnean Society

Editor-in-Chief, Biochemical Systematics and Ecology

Editorial Board, Phytochemistry, Phytotherapy Research, Physiological Entomology, Journal of Tropical Medicinal Plants, Natural Product Communications

Visiting Professor, Birkbeck College University of London, University of Greenwich and School of Pharmacy University of London. 

Role

Sustainable uses of plants; medicinal plants; plant–insect interactions; natural products, fungi, bio-control, economic botany, ethnobotany.

As Director of the Kew Innovation Unit I lead the co-ordination of cross-directorate projects that generate income for RBG Kew through the utilisation of the breath of expertise that RBG Kew staff have in different aspects of plant science and horticulture, based on their research of the diversity of the RBG Kew collections. My personal scientific research is focused on the research undertaken by the Sustainable Uses of Plants group. This includes research into the economic uses of plants/fungi, their potential as pharmaceutical and agrochemical leads, and as sources of sustainably-harvested products. This involves not only studying the chemistry of plants and fungi, the biological activities (e.g. diabetes, anti-microbial, HIV, anti-malarial, Alzheimer’s disease cancer, insecticidal, antifeedants and anti-inflammatory) of extracts and isolated compounds and using the new DNA based phylogenies to assist guide the selection of species, but also working with those growing the plants. The group also develops chemical authentication methods for use by companies, NGO’s, government bodies and by field workers to check the quality of plant-derived products being sold as medicines, cosmetics and functional foods. These projects often involve the development of practical aspects of benefit-sharing strategies with commercial and other collaborators that support plant conservation in developing countries. I have a keen research interest in furthering our understanding of the role plant-derived compounds play in plant-animal interactions, especially their role in the host selection behaviour of insects. This basic ecological knowledge can assist identification of plant-derived compounds that have use in pest control as well as in pharmaceutical research. Furthering our knowledge about the historical uses and potential new uses of plants assists support plant conservation and it is vital that there is dissemination of this knowledge in ways that engage with the public, especially the young. The majority of the work of this group is funded through research grants and commercial contracts.

Selected Recent Publications

  • Kite, G.C., Veitch, N.C., Boalch, M.E., Lewis, G.P., Leon, C.J. & Simmonds, M.S.J. (2009). Flavonol tetraglycosides from fruits of Styphnolobium japonicum (Leguminosae) and the authentication of Fructus Sophorae and Flos Sophorae. Phytochemistry 70:785–794.

  • Howes, M.-J.R., Kite, G.C. & Simmonds, M.S.J. (2009). Distinguishing Chinese star anise from Japanese star anise using thermal desorption-gas chromatography-mass spectrometry. J. Agric. Food Chem. 57: 5783-5789.

  • Kite, G.C. Porter, E.A. & Simmonds, M.S.J. (2007). Chromatographic behaviour of steroidal saponins studied by high-performance liquid chromatography–mass spectrometry. Journal of Chromatography A 1148: 177–183.

  • Kokubun, T., Irwin, D., Legg, M., Veitch, N.C. & Simmonds, M.S.J. (2007) Serialynic acid, a new phenol with an isopentenyne side chain from Antrodia serialis. Journal of Antibiotics 60: 285–288.

  • Stevenson, P.C. Veitch, N.C. & Simmonds, M.S.J. (2007). Polyoxygenated cyclohexane derivatives and other constituents from Kaempferia rotunda L. Phytochemistry 68: 1579–1586.

Selected Earlier Publications

  • Howes, M.-J., Simmonds, M.S.J. & Kite, G.C. (2004). Evaluation of the quality of sandalwood essential oils by gas chromatography-mass spectrometry. Journal of Chromatography A 1028: 307-312.

  • Kite, G.C., Howes, M-J.R. & Simmonds, M.S.J. (2004). Metabolomic analysis of saponins in crude extracts of Quillaja saponaria by liquid chromatography/mass spectrometry for product authentication. Rapid Communications in Mass Spectrometry 18:2859-2870.

  • Simmonds, M.S.J., Jarvis, A.P., Johnson, S., Jones, G.R. & Morgan, E.D. (2004). Comparison of anti-feedant and insecticidal activity of nimbin and salannin photo-oxidation products with neem (Azadirachtin indica) limonoids. Pest Management Science 60: 459-464.

  • Kite, G.C., Howes, M.-J.R., Leon, C. & Simmonds, M.S.J. (2003). Liquid chromatography – mass spectrometry of malonyl-ginsenosides in the authentication of ginseng. Rapid Communications in Mass Spectrometry 17: 238-244.

  • Simmonds, M.S.J. & Stevenson, P.C. (2001). Effects of isoflavonoids from Cicer on larvae of Helicoverpa armigera. Journal of Chemical Ecology 27 965-977.