Reynolds, Thomas

Job Title

Senior Research Fellow

Department

Jodrell Laboratory

Section

Sustainable Uses

Science Teams:

Qualifications & Appointments

BSc, Univ. London, 1954

MSc, Univ. London, 1957

DIC, Imperial College, 1957.

Role

Phytochemistry of Aloes and other plants; biological activity of plant constituents; structure-activity relations of plant chemicals.

Comparative phytochemistry of Aloe based on surveys of distribution of phenolic compounds in the leaf exudates, chiefly anthraquinones and chromones. Isolation and structural identification of unknown compounds from these plants. Preparation of samples of selected compounds for investigation of biological activity. Compilation of a database of literature on Aloaceae. Preparation of reviews from the literature on Aloe gel chemical characters and therapeutic activities. Review of the steroidal and isosteroidal alkaloids from Fritillaria species from the literature and also extraction of compounds from living material held at Kew and examination by LC/MS. This is in conjunction with a large-scale cytological study of the genus being undertaken elsewhere in the Jodrell Laboratory. Some of the species are used in Traditional Chinese Medicine.

Selected Earlier Publications

  • Reynolds, T. (2005). Hemlock alkaloids from Socrates to poison aloes. Phytochemistry 66: 1399-1406.

  • Reynolds, T. (ed) (2004). Aloes - the genus Aloe. Boca Raton, London, New York, Washington, D.C.: CRC Press.

  • Reynolds, T. (2004). Aloe chemistry. In Reynolds, T. (ed), Aloes - the genus Aloe. CRC Press; Boca Raton, London, New York, Washington, D.C. 39-74.

  • Reynolds, T. (2004). Analytical methodology: the exudate . In Reynolds, T. (ed), Aloes - the genus Aloe. CRC Press; Boca Raton, London, New York, Washington, D.C. 127-138.

  • Reynolds, T. (2002). Aloe Chemistry. Current Topics in Phytochemistry 5, 235-254.

  • Reynolds, T. (2000). Chemical constituents of Aloes. Haworthiad 14: 96-99.

  • Reynolds, T. & Dweck, A.C. (1999). Aloe vera leaf gel:a review update. Journal of Ethnopharmacology 68: 3-37.

  • Reynolds, T. (1998). Aloe vera gel: what are the active ingredients? Proc. Active Ingred. Conf., Paris, 85-93.

  • Reynolds, T. (1997). Comparative chromatographic patterns of leaf exudate components from Aloe Section Pachydendron Haw. Botanical Journal of the Linnean Society 125: 45-70.

  • Reynolds, T. (1997). Looking for natural sunscreens. Proc. Active Ingred. Conf., Paris, 109-118.