Geoffrey Kite

Kite, Geoffrey C.

Job Title

Research Phytochemist (Mass Spectrometry)

Department

Jodrell Laboratory

Section

Sustainable Uses

Science Teams:

Joined Kew: 1986

Qualifications & Appointments

BSc, Botany, Univ. London, 1982

PhD, Univ. London, 1986

ARPS, Royal Photographic Society (1986)

Committee, Phytochemical Society of Europe (1988-1991)

Committee, VAM Mass Spectrometry Working Group (2004-2006)

Production Editor, Kew Scientist (1992 - to date)

Editor, Specialist Science & Conservation News, Kew website (2010 - to date)

Role

Use of mass spectrometry to study plant chemical diversity.

Responsible for the development of mass spectrometry in the Jodrell Laboratory in the analysis of ‘small molecules’ in plants. Techniques utilizing mass spectrometry are fundamental to Kew's research in systematic phytochemistry, natural product discovery and the chemical authentication of plant extracts or products, and also contribute to many studies on the sustainable uses of plants and answering enquiries. Current instrumentation comprises a high resolution liquid chromatograph–hybrid ion trap/orbitrap mass spectrometer, a liquid chromatograph–quadrupole mass spectrometer and a gas chromatograph–quadrupole mass spectrometer with thermal desorption capability. Systematic phytochemical applications are being undertaken in Leguminosae, monocots, Malpighiales, Myrtaceae and Lamiaceae in collaboration with taxonomists and phytochemists at Kew and from other institutions. Chemical authentication of plant extracts or products focuses on issues arising from plants or extracts being traded in the UK, while enquiries are often concerned with poisoning cases.

Also responsible for producing Kew Scientist and the more specialist Science & Conservation News stories on the Kew website.

Selected Recent Publications

  • Kite, G.C. & Veitch, N.C. (2011). Identification of common glycosyl groups of flavonoid O-glycosides by serial mass spectrometry of sodiated species. Rapid Communications in Mass Spectrometry 25: 2579–2590

  • Kite, G.C., Green, P.W.C, Veitch, N.C, Groves, M.C., Gasson, P.E. & Simmonds, M.S.J. (2010). Dalnigrin, a neoflavonoid marker for the identification of Brazilian rosewood (Dalbergia nigra) in CITES enforcement. Phytochemistry 71: 1122-1131.

  • Kite, G.C. & Veitch, N.C. (2009). Assigning glucose or galactose as the primary glycosidic sugar in 3-O-mono-, di- and triglycosides of kaempferol using negative ion electrospray and serial mass spectrometry. Rapid Communications in Mass Spectrometry 23: 3125-3132.

  • Kite, G.C., Porter, E.A. & Simmonds, M.S.J. (2007). Chromatographic behaviour of steroidal saponins studied by high-performance liquid chromatography–mass spectrometry. Journal of Chromatography A 1148: 177–183.

  • Kite, G.C., Stoneham, C.A., Veitch, N.C., Stein, B.K. & Whitwell, K.E. (2006). Application of liquid chromatography-mass spectrometry to the investigation of poisoning by Oenanthe crocata. Journal of Chromatography B 838: 63-70.

Selected Earlier Publications

  • Kite, G.C., Howes, M-J.R. & Simmonds M.S.J. (2004). Metabolomic analysis of saponins in crude extracts of Quillaja saponaria by liquid chromatography/mass spectrometry for product authentication. Rapid Communications in Mass Spectrometry 18: 2859-2870.

  • Kite, G.C., Howes, M.-J. R., Leon, C. & Simmonds, M.S.J. (2003). Liquid chromatography – mass spectrometry of malonyl-ginsenosides in the authentication of ginseng. Rapid Communications in Mass Spectrometry 17: 238-244.

  • Kite, G.C., Veitch, N.C, Grayer, R.J. & Simmonds, M.S.J. (2003). The use of hyphenated techniques in comparative phytochemical studies of legumes. Biochemical Systematics and Ecology 31: 813-843.

  • Kite, G.C., Yule, M.A., Leon, C. & Simmonds, M.S.J. (2002). Detecting aristolochic acids in herbal remedies by liquid chromatography/serial mass spectrometry. Rapid Communications in Mass Spectrometry 16: 585-590.

  • Kite G.C., Lawrence T.J. & Dauncey E.A. (2000). Detecting Taxus poisoning in horses using liquid chromatography/mass spectrometry. Veterinary and Human Toxicology 42:151-4.