Fang, Rui
Job TitleResearch Phytochemist
DepartmentJodrell Laboratory
SectionSustainable Uses
Science Teams:
Joined Kew: 2008
Foreign Language(s): Chinese (mother tongue)
Qualifications & Appointments
BSc / Biochemistry, South China Agricultural University 2001
PhD / Pharmacy, King’s College London, University of London 2006
Postdoctoral research, Pharmacy department, King’s College London 2007
Role
Quality control of traditional medicines via chromatography and spectrometry technologies; Chemosystematic implications of compounds found in Iris spp.
Phytochemical research of selected natural products based on their traditional use in the benefit areas and high-throughput screening results. In-vitro bioassay-guided fractionation leading to isolation of active compounds, which supports the development of new healthcare products. Structures of novel compounds determined mainly by means of MS (mass spectrometry) and 1D & 2D NMR (nuclear magnetic resonance) spectroscopic techniques.
Projects
Selected Recent Publications
Fang, R., Veitch, N.C., Kite, G.C., Howes, M.-J. R., Porter, E.A. & Simmonds, M.S.J. (2011). Glycosylated constituents of Iris fulva and Iris brevicaulis. Chemical & Pharmaceutical Bulletin 59(1): 124-8.
Fang, R., Houghton, P.J. & Hylands, P.J. (2008). Cytotoxic effects of compounds from Iris tectorum on human cancer cell lines. Journal of Ethnopharmacology 118(2): 257-263.
Houghton, P.J., Fang, R., Techatanawat, I., Steventon, G., Hylands, P.J. & Lee, C.C. (2007). The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity. Methods 42(4): 377-387.
Fang, R., Houghton, P.J., Luo, C. & Hylands, P.J. (2007). Isolation and structure determination of two triterpenes from Iris tectorum. Phytochemistry 68(9): 1242-1247.
Selected Earlier Publications
Fang, R. (2005). The principles and methods for the development of TCM quality control system. Chinese Journal of Information on Traditional Chinese Medicine 12(6): 3-5.
Zhu, X.-T., Jiang, Q.-Y., Fu, W.-L. & Fang, R. (2002). Effects of avian pancreatic polypeptide on the secretive functions of cultured hepatocytes of rats. Chinese Journal of Applied Physiology 18(4): 346.
